Dopaminergic neurotransmission via dopamine D1 receptors (D1Rs) is considered to play an important role not only in reward-based Smart Thermostat learning but also in aversive learning.The contextual and auditory cued fear conditioning tests involve the processing of classical fear conditioning and evaluates aversive learning memory.It is possible
We describe the case of a 78-year-old woman admitted to our emergency department for an acute onset Impotence Products of severe dyspnoea with inspiratory wheezing-like sounds.She denied fever, cough, voice change and pain.She referred a similar but less severe episode occurred spontaneously one year before, with complete resolution in few minutes
Raf Kinase Inhibitory Protein or RKIP was initially identified as a Raf-1 binding protein using the yeast 2-hybrid screen.RKIP inhibits the activation phosphorylation of MEK by Raf-1 by competitively inhibiting the binding of MEK to Raf-1 and thus exerting an inhibitory effect on the Raf-MEK-Erk pathway.RKIP has been identified as a metastasis supp
Abstract Patients on mechanical ventilation may receive intravenous fluids via restrictive or liberal fluid management.A clear and objective differentiation between restrictive and liberal fluid management strategies is lacking in the literature.The liberal approach has been described as involving fluid rates ranging from 1.2 to 12 times higher tha